Publications

    Journal articles

    1. F. Razak, S. Shin, F. Pogacar, H. Y. Jung, L. Pus, A. Moser, L. Lapointe-Shaw, T. Tang, J. L. Kwan, A. Weinerman, S. Rawal, V. Kushnir, D. Mak, D. Martin, K. G. Shojania, S. Bhatia, N. Daneman, P. Agarwal, G. Mukerji, M. Fralick, M. K. Kapral, M. Morgan, B. Wong, T. C. Y. Chan, A. A. Verma, “Modelling resource requirements and physician staffing to provide virtual urgent medical care for residents of long-term care homes: a cross-sectional study,” CMAJ Open, accepted 2020.
    2. M. G. Crowson, J. W. Lee, A. Hamour, R. Mahmood, V. Lin, D. L. Tucci, T. C. Y. Chan, “AutoAudio: Deep Learning for Automatic Audiogram Interpretation,” Journal of Medical Systems, accepted 2020.
    3. C. L. F. Sun, L. Karlsson, L. J. Morrison, S. C. Brooks, F. Folke, T. C. Y. Chan, “Effect of optimized vs guidelines-based AED placement on out-of-hospital cardiac arrest coverage: an in silico trial,” Journal of the American Heart Association, accepted 2020.
    4. M. G. Crowson, T. C. Y. Chan, “Machine learning as a catalyst for value-based health care,” Journal of Medical Systems, accepted 2020.
    5. M. G. Crowson, A. Hamour, V. Lin, J. M. Chen, T. C. Y. Chan, “Machine learning for pattern detection in cochlear implant FDA adverse event reports,” Cochlear Implants International, accepted 2020.
    6. S. Cheskes, S. L. McLeod, M. Nolan, P. Snobelen, C. Vaillancourt, S. C. Brooks, K. N. Dainty, T. C. Y. Chan, I. R. Drennan, “Rapid access to automated external defibrillators in rural and remote settings: A drone delivery feasibility study,” Journal of the American Heart Association, accepted 2020.
    7. T. C. Y. Chan, C. Fernandes, M. L. Puterman, “Points gained in football: Using Markov process-based value functions to assess team performance,” Operations Research, accepted 2020.
    8. K. H. B. Leung, C. L. F. Sun, M. Yang, K. S. Allan, N. Wong, T. C. Y. Chan, “Optimal in-hospital defibrillator placement,” Resuscitation, accepted 2020.
    9. A. Babier, R. Mahmood, A. L. McNiven, A. Diamant, T. C. Y. Chan, “The importance of evaluating the complete automated knowledge-based planning pipeline,” Physica Medica, Vol. 72, pp. 73-79, 2020.
    10. L. Karlsson, C. M. Hansen, C. Vourakis, C. L. F. Sun, S. Rajan, K. B. Sondergaard, L. Andelius, F. Lippert, G. H. Gislason, T. C. Y. Chan, C. Torp-Pedersen, F. Folke, “Improving bystander defibrillation in out-of-hospital cardiac arrests at home,” European Heart Journal: Acute Cardiovascular Care, accepted 2020.
    11. M. G. Crowson, P. Dixon, J. W. Lee, D. Shipp, T. Le, V. Lin, J. Chen, T. C. Y. Chan, “Predicting post-operative cochlear implant performance using supervised machine learning,” Otology & Neurotology, accepted 2020.
    12. B. Zhang, D. Ratano, L. J. Brochard, D. Georgopoulos, J. Duffin, M. Long, T. Schepens, I. Telias, A. S. Slutsky, E. C. Goligher, T. C. Y. Chan, “A physiology-based mathematical model for the selection of appropriate ventilator controls for lung and diaphragm protection,” Journal of Clinical Monitoring and Computing, accepted 2020.
    13. F. J. Mateen, K. H. B Leung, A. C. Vogel, A. Fode Cisse, T. C. Y. Chan, “A drone delivery network for antiepileptic drugs: a framework and modeling case study in a lowest-income country,” Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 114, pp. 308-314, 2020.
    14. J. J. Boutilier, T. C. Y. Chan, “Ambulance Emergency Response Optimization in developing countries,” Operations Research, accepted 2019.
    15. A. Babier, R. Mahmood, A. L. McNiven, A. Diamant, T. C. Y. Chan, “Knowledge-based automated planning with three-dimensional generative adversarial networks,” Medical Physics, Vol. 47, pp. 297-306, 2019.
    16. C. Fernandes, R. Yakubov, Y. Li, A. Prasad, T. C. Y. Chan, “Predicting plays in the National Football League,” Journal of Sports Analytics, Vol. 6, pp. 35-43, 2020.
    17. T. C. Y. Chan, N. Kaw, “Inverse optimization for the recovery of constraint parameters,” European Journal of Operational Research, Vol. 282, pp. 415-427, 2020.
    18. C. L. F. Sun, L. Karlsson, C. Torp-Pedersen, L. J. Morrison, S. C. Brooks. F. Folke, T. C. Y. Chan, “In silico trial of optimized versus real public defibrillator locations,” Journal of the American College of Cardiology, Vol. 74, pp. 1557-1567, 2019.
    19. M. G. Crowson, V. Lin, J. M. Chen, T. C. Y. Chan, “Machine learning & cochlear implantation – A structured review of opportunities and challenges,” Otology & Neurotology, Vol. 41, pp. e36-e45, 2020.
    20. M. Shuvy, M. Koh, F. Qiu, S. C. Brooks, T. C. Y. Chan, S. Cheskes, P. Dorian, G. Geri, S. Lin, D. C. Scales, D. T. Ko, “Health care utilization prior to out-of-hospital cardiac arrest: a population-based study,” Resuscitation, Vol. 141, pp. 158-165, 2019.
    21. K. E. C. Booth, T. C. Y. Chan, Y. Shalaby, “A mathematical optimization framework for expansion draft decision making and analysis,” Journal of Quantitative Analysis in Sports, Vol. 15, pp. 27-40, 2019.
    22. M. G. Crowson, J. Ranisau, A. Eskander, A. Babier, B. Xu, R. R. Kahmke, J. M. Chen, T. C. Y. Chan, “A contemporary review of machine learning in otolaryngology-head & neck surgery,” Laryngoscope, Vol. 130, pp. 45-51, 2020.
    23. J. Unkelbach, M. Alber, M. Bangert, R. Bokrantz, T. C. Y. Chan, J. Deasy, A. Fredriksson, B. L. Gorissen, M. van Herk, W. Liu, H. Mahmoudzadeh, O. Nohadani, J. V. Siebers, M. Witte, H. Xu, “Robust radiotherapy planning,” Physics in Medicine and Biology, Vol. 63, 22TR02, 2018.
    24. Y. Lee, R.-M. Ragguett, R. B. Mansur, J. J. Boutilier, J. D. Rosenblat, A. Trevizol, E. Brietzke, K. Lin, Z. Pan, M. Subramaniapillai, T. C. Y. Chan, D. Fus, C. Park, N. Musial, H. Zuckerman, V. C.-H. Chen, R. Ho, C. Rong, R. S. McIntyre, “Applications of machine learning algorithms to predict therapeutic outcomes in depression: a meta-analysis and systematic review,” Journal of Affective Disorders, Vol. 241, pp. 519-532, 2018.
    25. C. L. F. Sun, L. Karlsson, C. Torp-Pedersen, L. J. Morrison, F. Folke, T. C. Y. Chan, “Spatiotemporal AED optimization is generalizable,” Resuscitation, Vol. 131, pp. 101-107, 2018.
    26. T. C. Y. Chan, R. Singal, “A Bayesian regression approach to handicapping tennis players based on a rating system,” Journal of Quantitative Analysis in Sports, Vol. 14, pp. 131-141, 2018.
    27. A. Goli, J. J. Boutilier, M. B. Sharpe, T. Craig, T. C. Y. Chan, “A small number of objective function weight vectors is sufficient for automated treatment planning in prostate cancer,” Physics in Medicine and Biology, Vol. 63, 195004, 2018.
    28. A. Babier, J. J. Boutilier, M. B. Sharpe, A. L. McNiven, T. C. Y. Chan, “Inverse optimization of objective function weights for treatment planning using clinical dose-volume histograms,” Physics in Medicine and Biology, Vol. 63, 105004, 2018.
    29. A. Babier, J. J. Boutilier, A. L. McNiven, T. C. Y. Chan, “Knowledge-based automated planning for oropharyngeal cancer,” Medical Physics, Vol. 45, pp. 2875-2883, 2018.
    30. B. K. Eagen, T. C. Y. Chan, M. W. Carter, “Women’s College Hospital uses Operations Research to create an ambulatory clinic schedule,” Service Science, Vol. 10, pp. 230-240, 2018.
    31. I. Dayarian, T. C. Y. Chan, D. Jaffray, T. Stanescu, “A mixed-integer optimization approach for homogeneous magnet design,” Technology, Vol. 6, pp. 49-58, 2018.
    32. T. C. Y. Chan, T. Lee, “Trade-off preservation in inverse multi-objective convex optimization,” European Journal of Operational Research, Vol. 270, pp. 25-39, 2018.
    33. T. C. Y. Chan, D. Madras, M. L. Puterman, “Improving fairness in match play golf through enhanced handicap allocation,” Journal of Sports Analytics, Vol. 4, pp. 251-262, 2018.
    34. T. C. Y. Chan, D. Fearing, “Process flexibility in baseball: The value of positional flexibility,” Management Science, Vol. 65, pp. 1642-1666, 2017.
    35. T. C. Y. Chan, T. Lee, D. Terekhov, “Inverse optimization: Closed-form solutions, geometry, and goodness of fit,” Management Science, Vol. 65, pp. 1115-1135, 2019.
    36. M. Lee, D. Demirtas, J. E. Buick, M. J. Feldman, S. Cheskes, L. J. Morrison, T. C. Y. Chan, “Increased cardiac arrest survival and bystander intervention in enclosed pedestrian walkway systems,” Resuscitation, Vol. 118, pp. 1-7, 2017.
    37. T. C. Y. Chan, Z.-J. M. Shen, A. Siddiq, “Robust defibrillator deployment under cardiac arrest location uncertainty via row-and-column generation,” Operations Research, Vol. 66, pp. 358-379, 2018.
    38. T. C. Y. Chan, P. A. Mar, “Stability and continuity in robust optimization,” SIAM Journal on Optimization, Vol. 27, pp. 817-841, 2017. Online supplement
    39. B. D. Bradley, T. Jung, A. Tandon-Verma, B. Khoury, T. C. Y. Chan, Y.-L. Cheng, “Operations Research in Global Health: A scoping review with a focus on the themes of health equity and impact,” Health Research Policy and Systems, Vol. 15, 32, 2017.
    40. J. J. Boutilier, S. C. Brooks, A. Janmohamed, A. Byers, J. E. Buick, C. Zhan, A. P. Schoellig, S. Cheskes, L. J. Morrison, T. C. Y. Chan, “Optimizing a drone network to deliver automated external defibrillators,” Circulation, Vol. 135, pp. 2454-2465, 2017.
    41. C. L. F. Sun, S. C. Brooks, L. J. Morrison, T. C. Y. Chan, “Ranking businesses and municipal locations by spatiotemporal cardiac arrest risk to guide public defibrillator placement,” Circulation, Vol. 135, pp. 1104-1119, 2017.
    42. T. C. Y. Chan, “Rise and shock: Optimal defibrillator placement in a high-rise building,” Prehospital Emergency Care, Vol. 21, pp. 309-314, 2017.
    43. T. C. Y. Chan, R. Singal, “A Markov Decision Process-based handicap system for tennis,” Journal of Quantitative Analysis in Sports, Vol. 12, pp. 179-189, 2016.
    44. C. L. F. Sun, D. Demirtas, S. C. Brooks, L. J. Morrison, T. C. Y. Chan, “Overcoming spatial and temporal barriers to public access defibrillators via optimization,” Journal of the American College of Cardiology, Vol. 68, pp. 836-845, 2016.
    45. J. J. Boutilier, T. Craig, M. B. Sharpe, T. C. Y. Chan, “Sample size requirements for knowledge-based treatment planning,” Medical Physics, Vol. 43, 1212, 2016.
    46. T. C. Y. Chan, D. Demirtas, R. H. Kwon, “Optimizing the deployment of public access defibrillators,” Management Science, Vol. 62, pp. 3617-3635, 2016.
    47. H. Mahmoudzadeh, T. G. Purdie, T. C. Y. Chan, “Constraint generation methods for robust optimization in radiation therapy,” Operations Research for Health Care, Vol. 8, pp. 85-90, 2016.
    48. H. Li, N. Becker, S. Raman, T. C. Y. Chan, J.-P. Bissonnette, “The value of nodal information in predicting lung cancer relapse using 4DPET/4DCT,” Medical Physics, Vol. 42, 4727, 2015.
    49. H. Li, J. P. Bissonnette, T. Purdie, T. C. Y. Chan, “Robust PET-guided intensity-modulated radiation therapy,” Medical Physics, Vol. 42, 4863, 2015.
    50. V. V. Misic, T. C. Y. Chan, “The perils of adapting to dose errors in radiation therapy,” PLOS ONE, Vol. 10, e0125335, 2015.
    51. P. A. Mar, T. C. Y. Chan, “Adaptive and robust radiation therapy in the presence of drift,” Physics in Medicine and Biology, Vol. 60, pp. 3599-3615, 2015.
    52. H. Mahmoudzadeh, J. Lee, T. C. Y. Chan, T. G. Purdie, “Robust optimization methods for cardiac sparing in tangential breast IMRT,” Medical Physics, Vol. 42, 2212, 2015.
    53. J. J. Boutilier, T. Lee, T. Craig, M. B. Sharpe, T. C. Y. Chan, “Models for predicting objective function weights in prostate cancer IMRT,” Medical Physics, Vol. 42, 1586, 2015.
    54. T. C. Y. Chan, H. Mahmoudzadeh, T. G. Purdie, “A robust-CVaR optimization approach with application to breast cancer therapy,” European Journal of Operational Research, Vol. 238, pp. 876-885, 2014.
    55. B. D. Bradley, S. R. C. Howie, T. C. Y. Chan, Y.-L. Cheng, “Estimating oxygen needs for childhood pneumonia in developing country health systems: a new model for expecting the unexpected,” PLOS ONE, Vol. 9, e89872, 2014.
    56. T. C. Y. Chan, T. Craig, T. Lee, M. B. Sharpe, “Generalized inverse multi-objective optimization with application to cancer therapy,” Operations Research, Vol. 62, pp. 680-695, 2014.
    57. Y. Liu, T. C. Y. Chan, C.-G. Lee, Y. B. Cho, M. K. Islam, “A stochastic model for tumor geometry evolution during radiation therapy in cervical cancer,” Medical Physics, Vol. 41, 021705, 2014.
    58. S. D. O. Turner, D. A. Romero, P. Y. Zhang, C. H. Amon, T. C. Y. Chan, “A new mathematical programming approach to optimize wind farm layouts,” Renewable Energy, Vol. 63, pp. 674-680, 2014.
    59. T. Lee, M. Hummad, T. C. Y. Chan, T. Craig, M. B. Sharpe, “Predicting objective function weights from patient anatomy in prostate IMRT treatment planning,” Medical Physics, Vol. 40, 121706, 2013.
    60. S. D. O. Turner, T. C. Y. Chan, “Examining the LEED rating system using inverse optimization,” Journal of Solar Energy Engineering, Vol. 135, 040901, 2013.
    61. T. C. Y. Chan, “Deal or No Deal: A spreadsheet game to introduce decision making under uncertainty,” INFORMS Transactions on Education, Vol. 14, pp. 53-60, 2013.
    62. T. C. Y. Chan, V. V. Misic, “Adaptive and robust radiation therapy optimization for lung cancer,” European Journal of Operational Research, Vol. 231, pp. 745-756, 2013.
    63. A. A. Siddiq, S. C. Brooks, T. C. Y. Chan, “Modeling the impact of public access defibrillator range on public location cardiac arrest coverage,” Resuscitation, Vol. 84, pp. 904-909, 2013.
    64. T. C. Y. Chan, H. Li, G. Lebovic, S. K. Tang, J. Y. T. Chan, H. C. K. Cheng, L. J. Morrison, S. C. Brooks, “Identifying locations for public access defibrillators using mathematical optimization,” Circulation, Vol. 127, pp. 1801-1809, 2013.
    65. S. C. Brooks, J. H. Hsu, S. K. Tang, R. Jeyakumar, T. C. Y. Chan, “Determining risk for out-of-hospital cardiac arrest by location type in a Canadian urban setting to guide future public access defibrillator placement,” Annals of Emergency Medicine, Vol. 61, pp. 530-538, 2013.
    66. T. C. Y. Chan, “Motion-compensating intensity maps in intensity-modulated radiation therapy,” IIE Transactions on Healthcare Systems Engineering, Vol. 3, pp. 1-22, 2013.
    67. T. C. Y. Chan, J. A. Cho, D. C. Novati, “Quantifying the contribution of NHL player types to team performance,” Interfaces, Vol. 42, pp.131-145, 2012.
    68. T. C. Y. Chan, J. N. Tsitsiklis, T. Bortfeld, “Optimal margin and edge-enhanced intensity maps in the presence of motion and uncertainty,” Physics in Medicine and Biology, Vol. 55, pp. 515-533, 2010.
    69. C. Vrancic, A. Trofimov, T. C. Y. Chan, G. C. Sharp, T. Bortfeld, “Experimental evaluation of a robust optimization method for IMRT of moving targets,” Physics in Medicine and Biology, Vol. 54, pp. 2901-2914, 2009.
    70. T. Bortfeld, T. C. Y. Chan, A. Trofimov, J. N. Tsitsiklis, “Robust management of motion uncertainty in intensity modulated radiation therapy,” Operations Research, Vol. 56, pp. 1461-1473, 2008.
    71. A. Trofimov, C. Vrancic, T. C. Y. Chan, G. C. Sharp, T. Bortfeld, “Tumor trailing strategy for intensity-modulated radiation therapy of moving targets,” Medical Physics, Vol. 35, pp. 1718-1733, 2008.
    72. J. Unkelbach, T. C. Y. Chan, T. Bortfeld, “Accounting for range uncertainties in the optimization of intensity modulated proton therapy,” Physics in Medicine and Biology, Vol. 52, pp. 2755-2773, 2007.
    73. T. C. Y. Chan, T. Bortfeld, J. N. Tsitsiklis, “A robust approach to IMRT optimization,” Physics in Medicine and Biology, Vol. 51, pp. 2567-2583, 2006.

    Non-journal publications

    1. R. Mahmood, A. Babier, A. McNiven, A. Diamant, T. C. Y. Chan, “Automated treatment planning in radiation therapy using generative adversarial networks,” Proceedings of the 3rd Machine Learning for Healthcare Conference, PMLR, Vol. 85, pp. 484-499, 2018.
    2. T. C. Y. Chan and D. S. Fearing, “The value of flexibility in baseball roster construction,” Proceedings of the MIT Sloan Sports Analytics Conference 2013 , March 2013.
    3. S. D. O. Turner and T. C. Y. Chan, “Examining the LEED rating system using approximate inverse optimization,” Proceedings of the ASME 2012 International Mechanical Engineering Congress and Exposition, November 2012.
    4. T. C. Y. Chan and D. C. Novati, “Split personalities of NHL players: using clustering, projection and regression to measure individual point shares,” Proceedings of the MIT Sloan Sports Analytics Conference 2012, March 2012.
    5. T. C. Y. Chan and E. Feron, “Single and multi-agent exploration of a Markov decision process,” Proceedings of the 42nd Allerton Conference on Communication, Control, and Computing, October 2004.
    6. M. Ishutkina, T. Chan, E. Feron, “Development of an automated tracking system of tagged wild animals,” Proceedings of the Automation Technology for Off-Road Equipment Conference, October 2004.
    7. M. Dror and T. Chan, “Goofspiel,” Encyclopaedia of Mathematics, M. Hazewinkel (Ed.), Kluwer Academic Publishers, Amsterdam, The Netherlands, in press.

    Thesis

    1. T. C. Y. Chan, “Optimization under uncertainty in radiation therapy,” Ph.D. Thesis, Operations Research Center, Sloan School of Management, MIT, June 2007.
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